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High Dhea -s is big issue for me.In my 2 cases of thinning and baldness stages 4(NOORWOOD HAMILTON SCALE)need suggestions-One patient having DHEAS 5810ng/ml.His testosterone ,DHT and Prolactin levels are within normal range.
Other patient having 6410ng/ml dheas and progesterone somewhat higher with testosterone and oestrogen(E2) ,TSH within normal range.I think hydrocortisone in low doses help along with saw palmetto and appilication of oesrogen cream .What do you suggest?

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Comment by Dr Rushmini Maris Bt Ismail on May 6, 2010 at 3:44am
can try caffeine ...most of my patients gain hair .i also use llt laser in conjuction.hydrocortisone..I dont think its a good option to reduce his defence mechanism.What about progesrteron cream instead of estrogen...i heard a lot about saw palmetto but personally never use it yet.can anyone explain more regarding this
Comment by Dr Deepak Chaturvedi on February 5, 2010 at 5:21am
Hydrocortisone is a wonder drug but always been looked up with suspicion. In this patient the hydrocortisone should control the raised DHEA levels with the feed back inhibition. We need to be very clear in mentioning the sex of the patient whether Male or Female. Using Estrogen in males is again a matter of debate. I am not convinced yet, to use estrogen for the promotion of hair growth in Males.We have big example like some rockstars like M.J. who used lots of female hormones to take care of the voice , skin and hairs but ultimately there were lots of complications. Estrogen is predominantly a female hormone and I suggest should not be disturbed in males just for the cosmetic reasons. Saw palmetto surely helps the baldness in Males/Females. It also has some estrogenic properties so we have to be cautious. Same is with finesteride.The problems of loss of libido/energy is a big concern with finesteride.

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